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Opioid Peptides Janice C. Froehlich

Opioid Peptides

Janice C. Froehlich

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ISBN :
Kindle Edition
12 pages
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 About the Book 

Opioid peptides produced in the body act as neuromodulatorsthat modify the actions of other neurotransmittersin the central nervous system. By alteringthe electrical properties of their target neurons, therebymaking these neurons more difficult toMoreOpioid peptides produced in the body act as neuromodulatorsthat modify the actions of other neurotransmittersin the central nervous system. By alteringthe electrical properties of their target neurons, therebymaking these neurons more difficult to excite, opioidpeptides can influence the release of variousneurotransmitters. As a result of this modulation, opioidpeptides can—among other functions—inducepain relief and euphoria as well as affect certain behaviors,including alcohol consumption. Alcohol canactivate the opioid peptide system. This mechanismmay contribute to alcohol reinforcement and excessivealcohol consumption, because agents that inhibitthe opioid peptide system decrease alcohol selfadministrationin animals and reduce craving and alcoholconsumption in human alcoholics. Moreover, agenetically determined, increased responsiveness ofthe opioid system to alcohol may contribute to a predispositionfor alcoholism in some people.